{{11}}-in (1) suffix attached to a verb, first attested 1960 with sit-in (which probably was influenced by sit-down strike); used first of protests, extended c.1965 to any gathering.
{{12}}-in (2) chemical suffix, usually indicating a neutral substance, antibiotic, vitamin, or hormone; see -INE (Cf. -ine) (2).

Etymology dictionary. 2014.

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